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The Hidden Science: How Spinal Manipulation Interacts with Your Immune System

February 08, 2026

Curious about what's really happening inside your body during a chiropractic adjustment? Chiropractic adjustments initiate a sophisticated dialogue between your nervous system, immune system, and musculoskeletal structures—a biological conversation that scientists are only now beginning to map out. Cox Chiropractic Medicine Inc is excited to share this chiropractic research news with our patients.

YOUR BODY'S INTERNAL COMMUNICATION NETWORK

Picture your nervous system and immune cells as partners in constant communication, coordinating their responses to keep your body functioning at its best. As Dr. Taams explains in her research on neuroimmune interactions, your nervous and immune systems operate as a unified team—they're perpetually influencing one another, coordinating responses to keep you healthy and functioning optimally. (1) A goal of chiropractic care here at Cox Chiropractic Medicine Inc.

THE MECHANICAL MESSAGE

When you undergo spinal manipulation, the process goes far beyond mechanical adjustment —you're sending signals throughout your body. Research of late by Lewis and colleagues reveals that these "mechano-responsive" signals influence both bone and joint tissues in notable ways. (2) The controlled pressure applied during manipulation sends signals that your neuroimmune system can interpret, potentially dampening inflammation, changing pain pathways, and boosting tissue recovery.

REAL-WORLD IMPLICATIONS

What does this mean for you? Lutke Schipholt and her research team emphasize that understanding these neuroimmune interactions is vital for treating musculoskeletal conditions effectively. When chiropractors like yours at Cox Chiropractic Medicine Inc deliver specific manipulations, we're potentially influencing your immune responses at the site of injury or dysfunction—going beyond symptom relief to target the root inflammatory mechanisms. (3) This explains why many chiropractic clients report benefits beyond pain relief, including improved mobility, less stiffness, and even enhanced overall wellness. Your chiropractic spinal manipulation at Cox Chiropractic Medicine Inc isn't just moving something back into place; it could well be triggering a cascade of beneficial biological responses throughout interconnected body systems.

THE BOTTOM LINE

The science is exploring and reporting on what many chiropractic patients have experienced firsthand: spinal manipulation works through multiple pathways simultaneously. By understanding how mechanical forces impact neuroimmune cross-talk, we're gaining deeper insight into why chiropractic care can be such a beneficial approach for a variety of musculoskeletal conditions.

CONTACT Cox Chiropractic Medicine Inc

Listen to this PODCAST with Dr. James Cox on The Back Doctors Podcast with Dr. Michael Johnson as he describes the interaction of the immune system in more detail and the benefit of The Cox® Technic System of Spinal Pain Management for spine pain sufferers.

Make your Fort Wayne chiropractic appointment soon.