Healthy News June 2022 BACK PAIN and INFLAMMATION: Link & Test The examination for the diagnosis of back pain conditions has a new tool: urine testing! Why? Inflammation. Inflammation can be detected via serum tests like this that test for biomarker activity. The association between inflammation and back pain has been investigated. A rat study reported that, compared to sham treatment, manipulation and mobilization relieved sciatic radicular pain by potentially reducing neuroinflammation and inhibiting nitric oxide synthase expression. (1) Lately, chiropractic researchers have investigated specifically the outcome of chiropractic care on levels of the biomarker cytokine called tumor necrosis factor alpha (TNF-α) via urine tests. Described as a potent pro-inflammatory cytokine closely linked with intervertebral disc degeneration that may spark other cytokines’ (interleukin-6 or interleukin-1β) reactions as well, TNF-α levels were found to be elevated in patients with severe sciatica and chronic low back pain compared with milder symptomatic patients and healthy volunteers. Particularly, the urine tests of chronic low back pain patients found significantly higher baseline levels of TNF-α. The positive news: These levels were significantly lower after 4-6 weeks of chiropractic care! These levels did not link to pain intensity or disability. (2) Chiropractic care including spinal manipulation like the gentle form of Cox® Technic Flexion Distraction Decompression your Fort Wayne chiropractor uses has been experienced as pain-relieving in a mean of 12 visits and 30 days. (3) Bring your back pain and its related inflammation to Cox Chiropractic Medicine Inc! Listen to this PODCAST with Dr. Jeremy Heidt on The Back Doctors Podcast with Dr. Michael Johnson as he details his pain-alleviating chiropractic care with the Cox® Technic System of Spinal Pain Management of a female patient with severe sciatica. Fort Wayne CHIROPRACTIC TIP OF THE MONTH: The Anti-Inflammatory Blueberry Researchers have described the blueberry as anti-inflammatory as well as anti-obesity, anti-cancer, anti-oxidant, neuroprotective and more. Studies have demonstrated that the blueberry facilitated how nuclear receptors act. (4) More specifically, the anti-inflammatory action of the blueberry was found to inhibit inflammation by reducing the production of inflammatory factors and enhancing immunity. The main targets of the blueberry’s anti-inflammatory efforts were TNF, ESR1, AGTR1 and IGF1. (5) Notice TNF is in that list? Cox Chiropractic Medicine Inc hopes you like blueberries! They are good for you, our Fort Wayne back pain patient, and all of us. CONTACT Cox Chiropractic Medicine Inc Thank you for entrusting us with your spinal health. Schedule your Fort Wayne chiropractic appointment with Cox Chiropractic Medicine Inc now! "This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."