Cox Chiropractic Medicine Inc Treats Back Pain and Its Inflammatory Process02/26/2020Red. Swollen. Hot. Painful. Signs of inflammation that no Fort Wayne back pain patient wants to suffer. Cox Chiropractic Medicine Inc delivers chiropractic services to decrease back pain by recognizing and dealing with any related inflammation. INFLAMMATION AND BACK PAIN RELATED How can you deduce if there’s inflammation? Like anything else, researchers look for ways to measure it. To measure inflammation, researchers look for inflammatory biomarkers, biological markers like tumor necrosis factor alpha (TNF-α), C-reactive protein (CRP), and interleukin-6, interleukin-1β, that showed an increase. Researchers have uncovered that chronic inflammation raised cytokine production and activated pro-inflammatory pathways that may lead to non-specific low back pain. (1) Researchers observed systemic inflammation in chronic LBP and may influence transition from acute to persistent low back pain. Specifically, CRP was discovered to be elevated in acute low back pain patients and not in control patients. TNF was greater in back pain patients particularly in patients with depression. (2) Since researchers have already documented that inflammation is tied to back pain, Cox Chiropractic Medicine Inc knows that inflammation must be decreased to help in reducing Fort Wayne back pain. HOW TO STOP INFLAMMATION Well, first, know what inflammation does. Researchers used lipopolysaccharide (LPS) to create intervertebral disc degeneration in experiments. They want to see what may potentially reduce the generated back pain that comes with it and/or even avert the degeneration initially so we humans do not have to suffer low back pain at all! That’s a tough call though, Cox Chiropractic Medicine Inc understands. But follow this: researchers used LPS to create the degeneration that preceded low back pain. They discovered that procyanidin B3 (PRO-B3) seen in our diets blocked the production of inflammatory markers - tumor necrosis factor α (TNF-Α), interleukin-6 (IL-6), prostaglandin E2 (PGE2) and nitric oxide – linked to disc degeneration. It also prevented the loss of the disc’s gelatinous nucleus pulposus cells and structural damage of its anulus fibrosus (outer rings of disc). What does all this signify to researchers looking for a way to prevent degenerative disc degeneration (DDD)? PRO-B3 may be considered as a treatment agent for intervertebral disc degeneration (IVDD). This is a welcome bit of information for those 80% of us adults who are on track to get IVDD, a major cause of low back pain. (3) Another recent paper described that the p38 MAPK inflammatory pathway may be able to postpone DDD using the tyrosine kinase inhibitor, Genistein. (4) That is encouraging for the treatment of Fort Wayne back pain and inflammation. Vitamin D FOR INFLAMMATION Research states that vitamin D deficiency is associated with low back pain that is stronger in younger women and in those with more severe deficiency. (5) Vitamin D deficiency is connected to lumbar disc disease and more severe low back pain in postmenopausal women. (6) Let us talk about your vitamin D status at your next Fort Wayne chiropractic appointment. CONTACT Cox Chiropractic Medicine Inc Listen to this PODCAST with Dr. Sarah Murrow on The Back Doctors Podcast with Dr. Michael Johnson. In this episode, Dr. Murrow and her patient present how the Cox® Technic System alleviated back pain due to disc bulges.Schedule your next Fort Wayne chiropractic appointment with Cox Chiropractic Medicine Inc to get rid of those inflammation markers of red, hot, swollen and painful that are so bothersome to your spinal nerves inciting Fort Wayne low back pain. « View All Featured Articles"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."