Fort Wayne Pain and Inflammation Helped by Spinal Manipulation09/21/2021Pain and inflammation are known companions. Spinal manipulation has been used to decrease spine pain, back pain, neck pain, arm pain, and leg pain. New studies show that the effect of spinal manipulation may extend beyond the spine to potentially mediate inflammation and its influence on spine pain. Cox Chiropractic Medicine Inc views improvement in our spine pain patients in several ways: pain reduction, function improvement, etc. The functions of inflammation in back pain and of spinal manipulation in reducing that pain is key to the Fort Wayne chiropractic treatment plan. BIOMARKERS Biomarkers are quantifiable indicators of body function via tests like blood pressure, urine testing, blood testing, imaging, etc. Biomarkers can indicate normal and abnormal processes taking place in the body. In the realm of back pain, researchers have been looking to blood testable biomarkers like tumor necrosis factor (TNFα), interleukin-1 β (IL-1β), IL-6, IL-2, interferon (IFN), IL-1 receptor antagonist (IL-1RA), TNF soluble receptor type 2 (sTNFR2) and IL-10 to tell the story. A recent biomarker test is brain imaging. Why brain? Researchers realize that chronic back pain certainly alters the spine and believe that it alters the brain structure. Brain imaging is a non-invasive biomarker able to produce brain resting-state functional connectivity to analyze such variations. (1) Researchers continue coming up with new tests! Cox Chiropractic Medicine Inc is observing these biomarker findings watchfully. BIOMARKER TESTING FOR BACK PAIN As low back pain continues to dominate healthcare as one of the most significant contributors to disability globally, researchers are studying biomarkers and their role in low back pain. Researchers wondered if there was a variance in the inflammatory profiles of nonspecific acute and chronic low back pain sufferers. They discovered a distinct difference in that there was a disparity between pro-inflammatory and anti-inflammatory mediator levels leaning toward an overproduction of proinflammatory components in both types of patients. (2) Another report revealed that C-reactive protein in patients with acute non-specific low back pain and TNF-α in chronic non-specific low back pain patients were higher. (3) These types of tests may help your Fort Wayne chiropractor follow your back pain in a novel way. BIOMARKER TESTING OF BACK PAIN RESPONSE TO SPINAL MANIPULATION The chiropractic treatment plan at Cox Chiropractic Medicine Inc currently is based on gentle spinal manipulation to relieve pain. A blood test study for biomarkers taken at the start of and 2 weeks after such spinal manipulative treatment documented significant (though limited and diverse) changes in the production of several biomarkers in acute and chronic back pain patients. Pain and disability scores dropped too. (4) These are encouraging findings for the use of spinal manipulation for back pain. Cox Chiropractic Medicine Inc is excited to see more information about biomarker-level changes with Fort Wayne spinal manipulation! CONTACT Cox Chiropractic Medicine Inc Listen to this PODCAST with Dr. James Cox on The Back Doctors Podcast with Dr. Michael Johnson as he discusses how use of chiropractic spinal manipulation and Cox® Technic Flexion Distraction may well surpass pain relief. Set up your Fort Wayne chiropractic appointment now. Daily, pain and inflammation come through our door together. Our treatment helps reduce their impact on the lives of our Fort Wayne chiropractic patients. « View All Spine Articles"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."